Knowledge-based translational medicine is a rapidly growing discipline in biomedical research and aims to expedite the discovery of new diagnostic tools and treatments by using a multi-disciplinary, highly collaborative, "bench-to-bedside" approach. Large amounts of multi-omics, imaging (medical and molecular) and clinical data can now be captured for given patient populations. In addition to the challenges of data curation and harmonisation, new computational methods are required to identify molecular signatures that suggest disease subtype. These signatures may be predictive of outcome or progression, and impact on disease management by suggesting personalised therapeutic strategies for patients. Such approaches will further the development of a new taxonomy of disease.
In the TransMed COSI meeting, we will explore the current status of computational biology approaches within the field of translational medicine.
Information of previous TransMed meeting(s) can be found here.
Link to the ISMB/ECCB 2023 website is: here.
The TransMed 2023 meeting takes place in Lyon, France, on July 23-27, 2023, during the ISMB/ECCB 2023 conference.
Topics of interest
Topics of interest include, but are not limited to:
* Clinical and molecular data storage and integration infrastructure, including: data warehousing for translational medicine, multi-‘omics and clinical data integration, data visualization in translational medicine
* Curation and harmonization of clinical, ‘omics and imaging data, including: standards and ontologies in translational medicine, biomedical text mining and semantic representation
* Data analytics for patient stratification, biomarker and target discovery, including: disease subtype discovery, Electronic Health Records integration, translational imaging, multi-scale modelling, high performance and cloud computing in translational medicine, mathematical modelling for disease processes, pathways and networks
* Computational approaches for target selection and drug discovery, including: druggability assessment and target selection, polypharmacology, drug reuse, chemical library design, virtual screening technologies, drug discovery enabler pipelines and databases, chemical tool analysis
* ADME/PK and Tox models, including: databases and modeling approaches for ADME and PK, machine learning approaches to predicting toxicity, modeling of pharmacokinetics to man and model organism utility models
* Translational Medicine Informatics Applications/Case Studies, including: Next generation sequencing annotation and biomedicine applications, clinical data integration and application
Prof. Alfonso Valencia, Barcelona Supercomputing Center (BSC), Spanish National Bioinformatics Institute (INB-ISCIII), ELIXIR-ES and IMPaCT
Biography: Prof. Alfonso Valencia is ICREA research Professor, Director of the Life Sciences Department of the Barcelona Supercomputing Center, Director of the Spanish National Bioinformatics Institute INB/ELIXIR-ES and coordinator of the data pillar of the Spanish Personalised Medicine intiative, IMPaCT. His research interest is the development of Computational Biology methods and their application to biomedical problems. Some of the computational methods he developed are considered pioneering work in areas such as biological text mining, protein coevolution, disease networks and more recently modelling cellular systems (digital twins). He participates in some of the key cancer related international consortia. In terms of community services, he is one of the initial promoters of the ELIXIR infrastructure, founder of the Spanish and International Bioinformatics networks and former president of ISCB, the international professional association of Bioinformaticians. He is Executive Editor of the main journal in the field (Bioinformatics OUP).
Please follow the abstract submission indications from the ISMB/ECCB 2023 website.
Detailed information can be found: here.
Please follow the registration page on the ISCB website.
Venkata Satagopam - Luxembourg Centre For Systems Biomedicine (LCSB), University of Luxembourg, Luxembourg
Reinhard Schneider - Luxembourg Centre For Systems Biomedicine (LCSB), University of Luxembourg, Luxembourg
Maria Secrier - University College London, UK
Wei Gu - Luxembourg Centre For Systems Biomedicine (LCSB), University of Luxembourg, Luxembourg
Irina Balaur - Luxembourg Centre For Systems Biomedicine (LCSB), University of Luxembourg, Luxembourg
Sanne Abeln - Vrije Universiteit Amsterdam, NL
Heba Sailem - King’s College London, UK
Irene Ong - University of Wisconsin-Madison, USA
Mansoor Saqi - King’s College London, UK
Meet the Organizing committee here.
Programme committee (alphabetical order)
Marcio Luis Acencio - Luxembourg Centre For Systems Biomedicine (LCSB), University of Luxembourg
Basel Alshaikhdeeb - Luxembourg Centre For Systems Biomedicine (LCSB), University of Luxembourg
Hanna Ćwiek-Kupczyńska - Luxembourg Centre For Systems Biomedicine (LCSB), University of Luxembourg
Soumyabrata Ghosh - Luxembourg Centre For Systems Biomedicine (LCSB), University of Luxembourg
Mirek Kratochvil - Luxembourg Centre For Systems Biomedicine (LCSB), University of Luxembourg
Shaman Narayanasamy - Luxembourg Centre For Systems Biomedicine (LCSB), University of Luxembourg
Xinhui Wang - Luxembourg Centre For Systems Biomedicine (LCSB), University of Luxembourg
If you have any questions, please do not hesitate to contact us by our slack workspace.
Linkedin: Translational Medical Informatics Group
Please check our page on open positions here. Alternatively, please feel free to contact us directly.
The current TransMed logo was designed by Belinda Hanson.